Archives of Critical Care Medicine

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Incisional Injection of Magnesium Sulfate for Post-Cesarean Section Pain Management

Shirin Pazoki 1 , Majid Golestani Eraghi 1 and Mehri Jamilian 2 , *
Authors Information
1 Department of Anesthesiology, Arak University of Medical Sciences, Arak, IR Iran
2 Department of Gynecology, Arak University of Medical Sciences, Arak, IR Iran
Article information
  • Archives of Critical Care Medicine: January 28, 2015, 1 (1); e524
  • Published Online: November 12, 2014
  • Article Type: Research Article
  • Received: January 1, 2014
  • Revised: February 25, 2014
  • Accepted: May 18, 2014
  • DOI: 10.5812/accm.524

To Cite: Pazoki S, Golestani Eraghi M, Jamilian M. Incisional Injection of Magnesium Sulfate for Post-Cesarean Section Pain Management, Arch Crit Care Med. 2015 ; 1(1):e524. doi: 10.5812/accm.524.

Copyright © 2015, Archives of Critical Care Medicine. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Miller MD, Lars I, Eriksson LA, Fleisher MD, Jeanine P, Wiener-Kronish MD, et al. Miller's Anesthesia. 2010; : 3312
  • 2. McDonnell NJ, Keating ML, Muchatuta NA, Pavy TJ, Paech MJ. Analgesia after caesarean delivery. Anaesth Intensive Care. 2009; 37(4): 539-51[PubMed]
  • 3. Apfelbaum JL, Chen C, Mehta SS, Gan TJ. Postoperative pain experience: results from a national survey suggest postoperative pain continues to be undermanaged. Anesth Analg. 2003; 97(2): 534-40[PubMed]
  • 4. Woolf CJ. Somatic pain--pathogenesis and prevention. Br J Anaesth. 1995; 75(2): 169-76[PubMed]
  • 5. Iwatsu O, Ushida T, Tani T, Lawand NB, Yamamoto H. Peripheral Administration of Magnesium Sulfate and Ketamine Hydrochloride Produces Hypesthesia to Mechanical Stimuli in Humans. J Health Sci. 2002; 48(1): 69-72[DOI]
  • 6. Cairns BE, Svensson P, Wang K, Hupfeld S, Graven-Nielsen T, Sessle BJ, et al. Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle. J Neurophysiol. 2003; 90(4): 2098-105[DOI][PubMed]
  • 7. Elshamaa HA, Ibrahim M, Eldesuky HI. Magnesium sulfate in femoral nerve block, does postoperative analgesia differ? A comparative study. Egypt J Anesth. 2013; 30(2): 169-73
  • 8. Ozcan PE, Tugrul S, Senturk NM, Uludag E, Cakar N, Telci L, et al. Role of magnesium sulfate in postoperative pain management for patients undergoing thoracotomy. J Cardiothorac Vasc Anesth. 2007; 21(6): 827-31[DOI][PubMed]
  • 9. Koinig H, Wallner T, Marhofer P, Andel H, Horauf K, Mayer N. Magnesium sulfate reduces intra- and postoperative analgesic requirements. Anesth Analg. 1998; 87(1): 206-10[PubMed]
  • 10. Ryu JH, Kang MH, Park KS, Do SH. Effects of magnesium sulphate on intraoperative anaesthetic requirements and postoperative analgesia in gynaecology patients receiving total intravenous anaesthesia. Br J Anaesth. 2008; 100(3): 397-403[DOI][PubMed]
  • 11. Levaux C, Bonhomme V, Dewandre PY, Brichant JF, Hans P. Effect of intra-operative magnesium sulphate on pain relief and patient comfort after major lumbar orthopaedic surgery. Anaesthesia. 2003; 58(2): 131-5[PubMed]
  • 12. Koo BN, Kil HK, Shin YS, Song JW, Hong YW. The clinical effects of intrathecal MgSO4 on spinal anesthesia and postoperative epidural analgesia in total knee replacement. Reg Anesth Pain Med. 2004; 29: 11[DOI]
  • 13. Tauzin-Fin P, Sesay M, Delort-Laval S, Krol-Houdek MC, Maurette P. Intravenous magnesium sulphate decreases postoperative tramadol requirement after radical prostatectomy. Eur J Anaesthesiol. 2006; 23(12): 1055-9[DOI][PubMed]
  • 14. Tauzin-Fin P, Sesay M, Svartz L, Krol-Houdek MC, Maurette P. Wound infiltration with magnesium sulphate and ropivacaine mixture reduces postoperative tramadol requirements after radical prostatectomy. Acta Anaesthesiol Scand. 2009; 53(4): 464-9[DOI][PubMed]
  • 15. Ghrab BE, Maatoug M, Kallel N, Khemakhem K, Chaari M, Kolsi K, et al. [Does combination of intrathecal magnesium sulfate and morphine improve postcaesarean section analgesia?]. Ann Fr Anesth Reanim. 2009; 28(5): 454-9[DOI][PubMed]
  • 16. Schulz-Stubner S, Wettmann G, Reyle-Hahn SM, Rossaint R. Magnesium as part of balanced general anaesthesia with propofol, remifentanil and mivacurium: a double-blind, randomized prospective study in 50 patients. Eur J Anaesthesiol. 2001; 18(11): 723-9[PubMed]
  • 17. Seyhan TO, Tugrul M, Sungur MO, Kayacan S, Telci L, Pembeci K, et al. Effects of three different dose regimens of magnesium on propofol requirements, haemodynamic variables and postoperative pain relief in gynaecological surgery. Br J Anaesth. 2006; 96(2): 247-52[DOI][PubMed]
  • 18. Vahabi A, Shoja T, Chaibakhsh S, Khak M, Saljoghi N. Effect of postoperative topical administration of magnesium sulfate on pain relief in paediatric adenotonsiiectomy: A Randomised controlled study. HK J Paediat. 2012; 17(1): 109-14
  • 19. Hung YC, Chen CY, Lirk P, Wang CF, Cheng JK, Chen CC, et al. Magnesium sulfate diminishes the effects of amide local anesthetics in rat sciatic-nerve block. Reg Anesth Pain Med. 2007; 32(4): 288-95[DOI][PubMed]
  • 20. Bondok RS, Abd El-Hady AM. Intra-articular magnesium is effective for postoperative analgesia in arthroscopic knee surgery. Br J Anaesth. 2006; 97(3): 389-92[DOI][PubMed]
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